Addressing the rising incidence of extrapulmonary tuberculosis (EPTB) in Egypt necessitates a multifaceted approach that incorporates enhanced screening measures and tailored treatment strategies. Implementing targeted screening programs in high-risk populations, such as immunocompromised individuals and those with a history of pulmonary TB, could significantly increase early detection rates. Furthermore, expanding access to diagnostic tools, such as ultrasound and biopsy techniques, will facilitate timely diagnosis of extrapulmonary sites, thereby reducing the burden of advanced disease. Healthcare providers should also receive ongoing training on the diverse presentation of EPTB, ensuring they remain vigilant in recognizing atypical symptoms.

On the treatment front, it is crucial to adopt a patient-centered care model that considers the unique needs of EPTB patients. Simplifying treatment protocols, ensuring adherence through community health programs, and integrating mental health support within TB services can markedly improve patient outcomes. Additionally, establishing multidisciplinary care teams allows for holistic management, encompassing physical health, psychosocial support, and socioeconomic assistance, thereby addressing barriers to effective treatment. These strategic recommendations, underpinned by robust data and community engagement, promise a significant advancement in tackling the challenges of extrapulmonary TB in Egypt.